122348
Based on recent scientific literature from late 2025/early 2026, the number refers specifically to the total count of Differentially Methylated Regions (DMRs) identified in a comprehensive study of colorectal adenoma subtypes.
The researchers used these 122,348 regions to create unique methylation "signatures" for different types of adenomas—specifically Sessile Serrated Lesions (SSL), Traditional Serrated Adenoma (TSA), and VA/TVA (Villous/Tubulovillous Adenoma). 122348
The study allowed for precise differentiation of molecular pathways that lead to colorectal cancer (CRC), reinforcing that distinct histological groups (SSL vs. TSA vs. VA) are driven by unique molecular machinery. If you are working on a similar research project, Based on recent scientific literature from late 2025/early
Each adenoma subtype was directly compared to normal tissue to identify unique methylation signatures. TSA vs
Here is a deep guide into this finding and its clinical significance. 1. Context: What Are the 122,348 DMRs?
the specific genes affected within those 122,348 regions? Find the original article for more detailed methodology?
