16748mp4 Apr 2026

The researchers tracked the movement of the protein

Published in (2016), this study uses live-cell imaging and mathematical modeling to understand how cells process signals from the Wnt pathway, which is critical for development and often deregulated in cancer. 16748mp4

The paper relies heavily on time-lapse movies to visualize these cellular dynamics. For example, Video 2 (referenced as part of eLife 16748) shows the accumulation and eventual egress of YFP- -catenin in cells treated with Wnt3a. The researchers tracked the movement of the protein

-catenin into the nucleus in real-time. They found that while -catenin into the nucleus in real-time

-catenin levels rise steadily after activation, the actual transcription of the target gene ( CCND1 ) occurs in "bursts" rather than a constant stream.

-catenin subcellular dynamics and cyclin D1 mRNA transcription during Wnt signaling

The "mp4" suffix in your query likely refers to the (such as Video 2 ) included with this open-access research, which are available for download in MPEG-4 format. Paper Overview: Quantifying