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If you are writing a formal essay, you might structure it as follows:

: In art, she is often depicted with a slight forward lean, symbolizing her reaching out to the "forsaken." This imagery spread through Spanish colonies, leading to major shrines like the Diocesan Shrine in Marikina and the Santa Ana Church in Manila. Desamparados

In a modern context, is a major canton in the San José province of Costa Rica. If you are writing a formal essay, you

: The devotion began in the 15th century when a brotherhood in Valencia dedicated itself to caring for the mentally ill and homeless. Desamparados