Dnaddr.mica_p-1-10.1.var [Chrome]

is a specific genetic variant identifier associated with the MICA (MHC class I polypeptide-related sequence A) gene . This nomenclature is primarily used in specialized genomic databases to catalog variations in the MICA protein, which plays a critical role in the human immune system's ability to detect stressed or infected cells. Core Function of the MICA Gene

: MICA serves as a ligand for the NKG2D receptor , which is found on Natural Killer (NK) cells and certain T cells [1, 2]. Dnaddr.Mica_P-1-10.1.var

: Under normal conditions, MICA is rarely expressed on healthy cells. However, it becomes highly expressed when cells undergo viral infection, malignant transformation (cancer), or heat shock [2, 3]. is a specific genetic variant identifier associated with

: Specific MICA alleles and variants are linked to increased susceptibility to conditions like Celiac disease , Psoriasis , and Type 1 Diabetes [2, 7]. : Under normal conditions, MICA is rarely expressed