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The ANSM classifies interactions into four increasing grades of importance:

: Should be avoided unless a strict benefit/risk assessment justifies it. The ANSM classifies interactions into four increasing grades

The most comprehensive and official resource for drug interactions at the "Contraindicated" (contre-indiqué) level in France is the , published by the Agence Nationale de Sécurité du Médicament (ANSM) . The ANSM classifies interactions into four increasing grades

: Absolute prohibition. The association must not be prescribed. The ANSM classifies interactions into four increasing grades

For real-time analysis of a specific prescription, you can also use professional tools like the . Thesaurus des interactions médicamenteuses - ANSM

The "Contraindicated" level is the highest of the four official clinical severity grades and has an absolute character; it must not be transgressed due to frequent and severe clinical consequences. Essential Official Documents

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