This guide outlines how to interpret Serum Protein Electrophoresis (SPEP) results, which separate blood proteins into specific fractions to help diagnose conditions like multiple myeloma, liver disease, or inflammation.
: Download the interpretation guide from FMC Tourcoing for a concise overview of quantitative values. This guide outlines how to interpret Serum Protein
You can find and download detailed clinical guides from these authoritative medical platforms: The Five Main Protein Fractions : The JNMG
Electrophoresis typically reveals five or six distinct peaks: Key Components Clinical Significance of Changes Main serum protein Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation
: Access the Cerba laboratory document for standard reference values and capillary electrophoresis details. The Five Main Protein Fractions
: The JNMG guide on anomalies provides specific indicators for bone pain or unexplained renal failure.
: Liver disease, kidney loss (nephrotic syndrome), or malnutrition. Increased : Dehydration. Alpha-1 Alpha-1 antitrypsin Increased : Acute inflammation. Alpha-2 Haptoglobin, Alpha-2 macroglobulin Increased : Acute phase reaction or nephrotic syndrome. Beta Transferrin, Complement Increased : Iron deficiency or high cholesterol. Two peaks ( ) are visible in capillary tests. Gamma Immunoglobulins (Antibodies)