Download | Maladies Bulleuses Acquises Pdf

Acquired bullous diseases () are a group of dermatological conditions characterized by the formation of blisters (bullae) on the skin and mucous membranes. These are primarily autoimmune in nature, where the immune system mistakenly attacks proteins that hold skin layers together. Key Types of Acquired Bullous Diseases

Medications like methotrexate or rituximab may be used for severe or recalcitrant cases to reduce steroid dependence. Download Maladies bulleuses acquises pdf

While the exact cause of the immune dysfunction is often unknown, several triggers have been identified: Acquired bullous diseases () are a group of

UV radiation, radiotherapy, or thermal burns. While the exact cause of the immune dysfunction

Blisters commonly occur on the trunk, limbs (flexural regions), groin, and lower abdomen.

Superpotent topical steroids (e.g., clobetasol propionate) are the first-line treatment for bullous pemphigoid. Systemic corticosteroids are often used for pemphigus.

Diagnosis is confirmed through direct immunofluorescence (DIF) of a skin biopsy, which detects specific antibody deposits, alongside histopathology to identify the level of skin cleavage. Causes and Triggers