Fibrous Dysplasia Of Bone Apr 2026

A triad of polyostotic FD, café-au-lait skin spots (often with jagged "Coast of Maine" borders), and hyperfunctioning endocrine issues like precocious puberty. Symptoms and Complications

Because the mutation happens after fertilization, only some cells carry it. This results in a patchy, variable distribution of the disease across the body. Clinical Classification fibrous dysplasia of bone

Affects multiple bones. This form typically presents earlier in childhood and is more severe. A triad of polyostotic FD, café-au-lait skin spots

Osteoblasts (bone-forming cells) fail to mature, producing disorganized "woven bone" instead of strong "lamellar bone". A triad of polyostotic FD

Fibrous dysplasia is categorized by how many bones it affects:

Affects a single bone. It accounts for about 70-80% of cases and is often asymptomatic until discovered incidentally on an X-ray.