: The drug targets a specific protein called USAG-1 (uterine sensitization-associated gene-1). In nature, USAG-1 acts as a "biological parking brake" that prevents dormant tooth buds in the human jaw from developing into full teeth after the adult set has grown.
Below is an overview of the development and science behind . TRG-035: The World's First Tooth Regrowth Drug NEWM-035
The drug was developed by , a spinoff from Kyoto University, led by Dr. Katsu Takahashi. : The drug targets a specific protein called
: Preclinical trials on mice and ferrets—chosen for their similar dental structures—successfully produced new teeth with normal enamel and root structures and no significant side effects. a spinoff from Kyoto University