[s1e7] Asylum Today

The doctor's spirit infects Sam with extreme rage, causing him to turn against Dean and even shoot him with rock salt.

It blurs the lines between the game and reality, ultimately showing the house being burned to the ground (within the game or a new reality) to provide a sense of finality to that arc. [S1E7] Asylum

In this DC Universe series, the episode focuses on the team's rescue mission to save Rachel’s birth mother from a mysterious psychiatric facility run by "The Organization". The doctor's spirit infects Sam with extreme rage,